Introduction to toxicology
An instructor-led online course | November 2022
Learn the principles of toxicology, hazard and risk assessment and toxicological testing
Course details
Is this course right for me?
What are my expected outcomes?
How will I learn?
Is this course right for me?
This course is right for you if:
✔️ You are a chemical safety advisor, a regulatory affairs professional or a scientist involved in R&D of new products
✔️ You have basic knowledge of biology or chemistry but need more background on toxicological principles to support your decisions
✔️ Your schedule allows you to allocate one hour to complete small homework assignments
What are my expected outcomes?
Upon completion of the course, you will better understand:
✔️ Basic principles of toxicology as well as guidelines for toxicological test methods
✔️ How chemicals affect the body and the fate of chemicals in the body
✔️ The importance of the choices you have to make to develop safe products
✔️ Hazard end-points and how different routes of exposure impact on toxicity
✔️ Hazard and risk assessments and the principles and rationale behind toxicological testing
How will I learn?
You will learn through instructor-led lectures with work examples of toxicological issues, mingled with small quizzes and exercises. For module 2, 3 and 4 you will also be given a small homework assignment.
During the course you will have time to discuss toxicological issues and best practices with your instructors and fellow participants.
The maximum number of participants is 14 to ensure high quality training and skill development.
Modules
This online course is divided into four 2-hour training sessions hosted from 10:00-12:00 CET.
Tuesday 8 November 2022 (10:00-12:00)
Module 1 | Basic toxicology and toxicological terms
What is toxicology? We will explain the relevance of toxicological knowledge and make you familiar with the most important terms in toxicology. Through examples we will define the dose response concept, including relevant dose metrics, and demonstrate how toxicity depends on exposure routes. We wrap up with an introduction to your homework assignment for module 2.
Friday 11 November 2022 (10:00-12:00)
Module 2 | Toxicodynamics and toxicokinetics
Review of the homework assignment. Then we proceed to explain the effects (toxicodynamics) and fate of chemical substances (toxicokinetics) in the body. This also includes a closer look at different types of effects considering toxicological mechanisms and modes of action (MoA). Brief introduction to homework for module 3.
Wednesday 16 November 2022 (10:00-12:00)
Module 3 | Testing and test guidelines
Review of homework task. We then describe the use of animal testing, how to get information and explain test design in the OECD test guidelines for various types of hazard testing and the principles for dose level selection. You will also learn about selection of test species, types of relevant animal examinations and how to apply a tiered approach in testing. We will touch briefly on alternative testing methods before finishing with introduction of your last homework assignment.
Tuesday 22 November 2022 (10:00-12:00)
Module 4 | Toxicological risk assessments
We go over the last homework exercise before we describe how toxicology is used in risk assessments. You will learn how to evaluate risks, for instance in connection with accidents and cases of pollution, and through examples we explain how to derive tolerable exposure levels. We also give a short introduction to Threshold of Toxicological Concern (TTC) before we wrap up the course with your final questions.
Instructor
Poul Bo Larsen has more than 30 years of experience in health risk assessment of chemicals. He has participated in working groups in the EU and the OECD and as the Danish representative in ECHA’s Risk Assessment Committee.
Poul’s comprehensive expertise includes regulatory toxicology, risk assessment, limit values, health impact of ambient air pollution, Occupational Exposure Limits (OEL), nanomaterials and REACH.
Chief Toxicologist
Brian Svend Nielsen has 20 years of professional experience in regulatory toxicology, chemicals regulation compliance and product safety assessment. He has expert knowledge of human toxicology in the areas of hazard identification, exposure assessment and risk assessment of chemicals.
Brian is an expert in the EU Medical Devices Regulation (MDR) and the REACH chemicals legislation.
Principal Toxicologist and European Registered Toxicologist (ERT)
Astrid Skovmand has a back-ground in in vivo pharmacology and toxicology and has research experience in reproductive and developmental toxicity of nanomaterials.
Astrid performs risk assessment of chemicals and particles. She is also helping major pharmaceutical companies with biocompatibility of medical devices as well as assessment of chemicals for endocrine disruptive properties.
Toxicologist, PhD
Pricing tiers
Regular Registration
€
1,050
excl. VAT
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Links to pertinent regulations and guidelines
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Handouts of course presentations
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Training certificate
Registration
5 online sessions: 03, 10, 17, 24 and 31 October 2019. Choose your preferred time below – morning or afternoon.
Price: € 600 excl. vat.
05.00-07.00 (UTC)
Time: 13.00-15.00 (UTC)
05.00-07.00 (UTC)
Register below to join our morning course sessions
Time: 13.00-15.00 (UTC)
Register below to join our afternoon course sessions
Register today!
Space is limited to the first 14 registrants.