Introduction to toxicology

Learn the principles of toxicology, hazard and risk assessment and toxicological testing

Instructor-led online course

This course will teach you the basic principles of toxicology, how chemicals affect the body and the fate of chemicals in the body. You will also hear about hazard end-points and how different routes of exposure impact on toxicity.

In addition, you will acquire an improved understanding of hazard and risk assessments and the principles and rationale behind toxicological testing.

Get a better understanding of toxicology

Knowledge of toxicology and the potential effects of chemical substances on human health is paramount when developing and marketing products – be it consumer products, pharmaceuticals, medical devices or other.

This four-module, instructor-led course will address the basic principles of toxicology and introduce you to the guidelines for toxicological test methods.

The training will give you a better understanding of toxicology and the importance of the choices you have to make to develop safe products.

Is this course right for me?

Are you a chemical safety advisor, a regulatory affairs professional or a scientist involved in R&D of new products?

Do you have basic knowledge of biology or chemistry but need more background on toxicological principles to support your decisions?

Does your schedule allow you to allocate one hour to complete small homework assignments for module 2, 3 and 4?

If yes, you can benefit from this online course.

Course details and important dates

The course is divided into four modules of two hours each. The training takes place on the following dates: 25 January, 28 January, 1 February and 4 February 2022

Sessions will take place 10:00 – 12:00 CET

You will learn through instructor-led lectures with work examples of toxicological issues, mingled with small quizzes and exercises. For module 2, 3 and 4 you will also be given a small homework assignment.

During the course you will have time to discuss toxicological issues and best practices with your instructors and fellow participants.

The maximum number of participants is 14 to ensure high quality training and skill development.

Registration deadlines
Early bird: 12 November 2021- €900 (excl. VAT)
Standard: 19 January 2022- €1050 (excl. VAT)

Tuesday, 25 January 2022
Module 1: Basic toxicology and toxicological terms
What is toxicology? We will explain the relevance of toxicological knowledge and make you familiar with the most important terms in toxicology. Through examples we will define the dose response concept, including relevant dose metrics, and demonstrate how toxicity depends on exposure routes. We wrap up with an introduction to your homework assignment for module 2.

Friday, 28 January 2022
Module 2: Toxicodynamics and toxicokinetics

Review of the homework assignment. Then we proceed to explain the effects (toxicodynamics) and fate of chemical substances (toxicokinetics) in the body. This also includes a closer look at different types of effects considering  toxicological mechanisms and modes of action (MoA). Brief introduction to homework for module 3.

Tuesday, 1 February 2022
Module 3: Testing and test guidelines
Review of homework task. We then describe the use of animal testing, how to get information and explain test design in the OECD test guidelines for various types of hazard testing and the principles for dose level selection. You will also learn about selection of test species, types of relevant animal examinations and how to apply a tiered approach in testing. We will touch briefly on alternative testing methods before finishing with introduction of your last homework assignment.

Friday, 4 February 2022
Module 4: Toxicological risk assessments
We go over the last homework exercise before we describe how toxicology is used in risk assessments. You will learn how to evaluate risks, for instance in connection with accidents and cases of pollution, and through examples we explain how to derive tolerable exposure levels. We also give a short introduction to Threshold of Toxicological Concern (TTC) before we wrap up the course with your final questions.

Four instructor-led online modules

900* excl. VAT
  • *Price will revert to €1050 (excl. VAT) after 12 November 2021
  • Includes links to pertinent regulations and guidelines, handouts of course presentations and training certificate.

Your training team

Poul Bo Larsen

Poul Bo Larsen has more than 30 years of experience in health risk assessment of chemicals. He has participated in working groups in the EU and the OECD and as the Danish representative in ECHA's Risk Assessment Committee.

Poul’s comprehensive expertise includes regulatory toxicology, risk assessment, limit values, health impact of ambient air pollution, Occupational Exposure Limits (OEL), nanomaterials and REACH.

Chief Toxicologist.

Brian Svend Nielsen

Brian Svend Nielsen has 20 years of professional experience in regulatory toxicology, chemicals regulation compliance and product safety assessment. He has expert knowledge of human toxicology in the areas of hazard identification, exposure assessment and risk assessment of chemicals.

Brian is an expert in the EU Medical Devices Regulation (MDR) and the REACH chemicals legislation.

Principal Toxicologist and European Registered Toxicologist (ERT).

Astrid Skovmand

Astrid Skovmand has a back-ground in in vivo pharmacology and toxicology and has research experience in reproductive and developmental toxicity of nanomaterials.

Astrid performs risk assessment of chemicals and particles. She is also helping major pharmaceutical companies with biocompatibility of medical devices as well as assessment of chemicals for endocrine disruptive properties.

Toxicologist, PhD.

Registration

5 online sessions: 03, 10, 17, 24 and 31 October 2019. Choose your preferred time below – morning or afternoon.

Price: € 600 excl. vat.